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These soft, bite-sized chews promote calmness, relaxation, and mood balance so your dog can live a happy, stress-free life.
Powerful, Calming Blend
Our Anxiety Chews are the ideal supplement to help ease dogs' stress, anxiety, and anger and promote relaxation in overly tense dogs. Crafted with various natural calming ingredients, our chew helps promote mood balance and relaxation, while maintaining mental alertness and cognitive function. These chews are perfect for those looking to help their dog deal with separation anxiety and combat the negative behaviors that often come along with it.*[4,5,10,11]
Not Your Average Anxiety Chew
We formulated our Anxiety Chew to include Hemp Seed Oil so your pup can experience overall wellness benefits. Rich in vitamins and minerals, Hemp Seed Oil has natural anti-inflammatory properties that may help ease inflammation in response to injuries, infections, allergies, and other ailments.[1,12]
Duck Flavored Chews
Often other chews and tablets are unpalatable and an unenjoyable experience for your dog. Our chews have undergone rigorous taste testing across all breeds to find the perfect blend of flavors so that your pooch will enjoy them and keep coming back for more!


Organic Chamomile
Chamomile is an herbal supplement that has been used due to its medicinal properties for centuries. Its effects come from natural plant compounds called terpenoids and flavonoids. Evidence shows that chamomile may ease your pup’s mood, as well as other benefits.
Dogs that exhibit restless, nervous, and hyperactive behaviors can especially benefit from this herbal ingredient.[3,4,5]


Valerian Root
Valerian root is a natural herb that has been said to block nerve transmissions in the brain that stimulate activity. Therefore, it has a calming effect on the brain.
Valerian root can help calm your canine and combat fears your dog may have, such as separation anxiety and unfamiliar situations.[6]


Organic Passion Flower
This perennial vine is known for its calming abilities and has been used for many years for medicinal purposes. Passionflower is now widely used as a calming remedy that helps to relax your dog’s mind, body, and even stomach.
It is a natural remedy that can work wonders for your dog as it lowers brain cell activity, helping your dog be in a calm and relaxed state.[7,8,9]


L-Theanine
This amino acid has been shown to have a positive effect on reducing anxiety and nervousness in dogs. L-theanine helps promote relaxation, which can be linked to lower blood pressure, as well as improved cognitive function and mood.
Since this natural amino acid has a calming effect, your pup may be less susceptible to displaying aggressive or destructive behavior.[10,11]

Additional Ingredients
Dried Brewer’s Yeast, Potato Flour, Potato Starch, Soy Lecithin, Cane Molasses, Glycerin, Purified Water, Powdered Cooked Beef, Safflower Oil, Natural Duck Flavor, Natural Flavor, Mixed Tocopherols, Ascorbic Acid (Vitamin C).
- Callaway, James, et al. Efficacy of dietary hempseed oil in patients with atopic dermatitis. Jour Dermatological Treatment. 2005. 16: 87-94. https://pubmed.ncbi.nlm.nih.gov/16019622/
- Zurier, Robert B, et al. Gamma-Linolenic Acid Treatment Of Rheumatoid Arthritis. Arthritis & Rheumatism. 1996. Vol. 39, No. 11. Pp 1808-1817. https://pubmed.ncbi.nlm.nih.gov/8912502/
- Gollakner, R. (n.d.). Chamomile: VCA Animal Hospitals. VCA Animal Hospitals. Retrieved April 6, 2023, from https://vcahospitals.com/know-your-pet/chamomile
- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895–901. https://doi.org/10.3892/mmr.2010.377
- Taylor, S., & Madden, J. (2016). The Effect of Pet Remedy on the Behaviour of the Domestic Dog (Canis familiaris). Animals : an open access journal from MDPI, 6(11), 64. https://doi.org/10.3390/ani6110064
- PetMD. (2017, August 16). Valerian root for dogs: Does it work? PetMD. Retrieved April 6, 2023, from https://www.petmd.com/dog/wellness/valerian-root-dogs-does-it-work
- Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam. J Clin Pharm Ther. 2001;26(5):369-373. https://pubmed.ncbi.nlm.nih.gov/11679026/
- Barbosa PR, Valvassori SS, Bordignon CL Jr, Kappel VD, Martins MR, Gavioli EC, et al. The aqueous extracts of Passiflora alata and Passiflora edulis reduce anxiety-related behaviors without affecting memory process in rats. J Med Food. 2008 Jun;11(2):282-8. https://pubmed.ncbi.nlm.nih.gov/18598170/
- Elsas SM, Rossi DJ, Raber J, White G, Seeley CA, Gregory WL, Mohr C, Pfankuch T, Soumyanath A. Passiflora incarnata L. (Passionflower) extracts elicit GABA currents in hippocampal neurons in vitro, and show anxiogenic and anticonvulsant effects in vivo, varying with extraction method. Phytomedicine. 2010;17(12):940-9. https://pubmed.ncbi.nlm.nih.gov/20382514/
- Gollakner, R. (n.d.). Chamomile: VCA Animal Hospitals. VCA Animal Hospitals. Retrieved April 6, 2023, from https://vcahospitals.com/know-your-pet/chamomile
- Srivastava, J. K., Shankar, E., & Gupta, S. (2010). Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports, 3(6), 895–901. https://doi.org/10.3892/mmr.2010.377
- Taylor, S., & Madden, J. (2016). The Effect of Pet Remedy on the Behaviour of the Domestic Dog (Canis familiaris). Animals : an open access journal from MDPI, 6(11), 64. https://doi.org/10.3390/ani6110064
A Happy, Calm Canine Means a Happy, Healthy Life

PupGrade Anxiety Chews are formulated to promote calmness and provide support for normal stress and separation anxiety. Our herbal and natural ingredients help support relaxation, all while maintaining mental alertness. As with any of our PupGrade products, we tested our formula extensively to ensure our Anxiety Chews are the best source and dosage of important ingredients your dog needs to live a happy, healthy, and calm life. And they taste amazing, too!