Joint Support
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These soft, bite-size chews provide the joint support your dog needs in a treat-like form.

9 IN 10 SAW AN IMPROVEMENT IN THEIR DOG'S MOBILITY

Unlike other joint supplements, our unique blend has been proven to improve mobility in just four weeks! Our powerful blend of ingredients helps to cushion joints and promote cartilage to rebuild and alleviate discomfort. Just take it from our customers—9 out of 10 surveyed customers saw an overall improvement in their dog's mobility.

MEAT FLAVORED CHEWS

Often other chews and tablets are unpalatable and an unenjoyable experience for your dog. Our chews have gone through rigorous taste testing across all breeds to find the perfect blend of flavors so that your pooch will enjoy them and keep coming back for more!

PERNA CANALICULUS

Perna is a Green-lipped mussel from the shores of New Zealand and is naturally rich in high levels of Glucosamine, Chondroitin, Hyaluronic acid, EFA’s & Amino acids. This entire blend makes it the perfect ingredient for protecting and healing your dog’s joints.

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Perna Canaliculus

Perna is a Green-lipped mussel from the shores of New Zealand and is naturally rich in Glucosamine, Chondroitin, Hyaluronic acid, EFA’s & Amino acids. This entire blend makes it the perfect ingredient for protecting and healing your dog’s joints.1,2,5

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Joint and hip pain relief "Secret Weapon"
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Supports lubrication of the joints
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100x+ more powerful than Omega-3 alone

Perna is rich in natural proteins, amino acids, vitamins, chelated minerals, and fatty acids.1,2,5,9

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Glucosamine and Chondroitin

Natural substances that work together to repair cartilage and other body tissues. Often recommended to add both to your arthritic dog's diet as a supplement or as a protective measure as your pet ages.

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Naturally boosts joint health, increasing mobility
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Has an anti-inflammatory effect, helping to reduce your dog's pain.
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Improves lubrication in your dog's joints.

Glucosamine is a safe and natural way to help improve your dog's joint function and quality of life. 1,4

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MSM

An organic sulfur compound that's well known for its joint health benefits. This antioxidant cleanses the bloodstream and flushes toxins from the cells.

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Natural analgesic and blocks the transfer of pain impulse
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Improves cellular uptake of nutrients
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Fights inflammation resulting from autoimmune reactions

Studies indicate that MSM improves cellular glucose uptake by improving cell permeability, thus balancing blood sugar levels and returning the pancreas to normal functioning. 3,6,7,8

Additional Ingredients

Manganese Gluconate, Brewer’s Yeast, Potato Flour, Can Molasses, Potato Starch, Purified Water, Soy Lecithin, Glycerin, Cooked Beef, Safflower Oil, Duck Flavor, Vitamin E, Ascorbic Acid, Sorbic Acid, Mixed Tocopherols.

  1. Perna, glucosamine, MSM, DMG, and antioxidants for advanced joint support in canines. Greenfield Animal Hospital. (n.d.). Retrieved from https://greenfieldvets.com/
  2. Perna: VCA Animal Hospital. Vca. (n.d.). Retrieved from https://vcahospitals.com/know-your-pet/perna#:~:text=What%20is%20perna%3F,cats%2C%20dogs%2C%20and%20horses.
  3. Kim, L. S., Axelrod, L. J., Howard, P., Buratovich, N., & Waters , R. F. (n.d.). Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: A pilot clinical trial. Osteoarthritis and cartilage. Retrieved from https://pubmed.ncbi.nlm.nih.gov/16309928/
  4. Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and chondroitin use in canines for osteoarthritis: A Review. Open veterinary journal. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356289/
  5. Bierer, T. L., & Bui, L. M. (2002, June 1). Improvement of arthritic signs in dogs fed green-lipped mussel (Perna canaliculus). OUP Academic. Retrieved from https://academic.oup.com/jn/article/132/6/1634S/4687864
  6. Debbi, E. M., Agar, G., Fichman, G., Ziv, Y. B., Kardosh, R., Halperin, N., Elbaz, A., Beer, Y., & Debi, R. (2011, June 27). Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: A randomized controlled study. BMC complementary and alternative medicine. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141601/
  7. Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017, March 16). Methylsulfonylmethane: Applications and safety of a novel dietary supplement. Nutrients. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
  8. Kabil O, Vitvitsky V, Banerjee R. Sulfur as a signaling nutrient through hydrogen sulfide. Annu Rev Nutr. 2014;34:171-205. doi: 10.1146/annurev-nutr-071813-105654. PMID: 25033061; PMCID: PMC4684266. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684266/
  9. Whitehouse, M. W., Macrides, T. A., Kalafatis, N., Betts, W. H., Haynes, D. R., & Broadbent, J. (1997). Anti-inflammatory activity of a lipid fraction (lyprinol) from the NZ green-lipped mussel. Inflammopharmacology, 5(3), 237–246. https://doi.org/10.1007/s10787-997-0002-0

Product FAQ

  • WHAT IS THIS SUPPLEMENT FOR? DOES IT HAVE THE CORRECT DOSAGE FOR MY DOG’S NEEDS?

    PupGrade Joint Support is a chewable supplement for dogs and puppies of all breeds, sizes, ages, and activity levels. Suitable for everyday canine health.

    Our Joint Support is a research-backed formula with just the right amount of essential nutrients to help keep your pup mobile and lively.

  • HOW DO I FEED THIS SUPPLEMENT TO MY DOG?

    We recommend following these directions for use:

    • 1 Chew: per 25 lbs.
    • Extra Support: double dosage first 4 weeks.
    • >1 Chew Daily: divide between AM & PM.

    *This product is intended for intermittent or supplemental feeding only.

  • IS THIS SUPPLEMENT FREE OF GRAIN?

    We are a veterinarian-formulated brand you can trust. These chews are made with only the good stuff and are 100% junk free! We are proud to offer your pet savory, GMP-Certified chews free of grains, wheat, corn, artificial colors, dyes, or harmful preservatives.

  • HOW MANY CHEWS ARE IN THIS CONTAINER?

    Our Joint Support supplements offer 60 chews per container.

  • WHAT ARE THE INGREDIENTS INCLUDED IN THIS PRODUCT?

    Active Ingredients: Glucosamine, Methyl Sulfonyl Methane, Green Lipped Mussel, Chondroitin, and Manganese Gluconate.

    Additional Ingredients: Brewer’s Yeast, Potato Flour, Can Molasses, Potato Starch, Purified Water, Soy Lecithin, Glycerin, Cooked Beef, Safflower Oil, Duck Flavor, Vitamin E, Ascorbic Acid, Sorbic Acid, Mixed Tocopherols.

  • WHAT IS THE GUARANTEED ANALYSIS PER CHEW (5g)?
    • Calories: 18 Kcal
    • Crude Protein (Min): 18%
    • Crude Fat (Min): 12%
    • Crude Fiber (Max): 3%
    • Moisture (Max): 8%
  • ARE THESE CHEWS SAFE FOR MY DOG IF THEY HAVE SENSITIVITIES OR OTHER CONDITIONS?

    We understand that every dog has unique needs. That’s why we offer supplements tailored to address specific concerns, such as sensitive stomachs and diabetic conditions. Our supplements contain easily digestible ingredients and exclude common allergens.

    Consult with your veterinarian before giving this supplement to your dog if you have any concerns.

  • HOW DO I STORE THIS PRODUCT?

    Store in a cool, dry place. Ensure container lid is securely closed after each use.

9 IN 10 SAW AN IMPROVEMENT IN THEIR DOG'S MOBILITY

Product benefit featured image

Unlike other joint supplements, our unique blend has been proven to improve mobility in just four weeks! Our powerful blend of ingredients helps to cushion joints and promote cartilage to rebuild and alleviate discomfort. Just take it from our customers—9 out of 10 surveyed customers saw an overall improvement in their dog's mobility.

Chews That Keep Your Dog Moving

Chews That Keep Your Dog Moving

See The Difference With PupGrade’s Joint Support

Help your pup stay healthy and mobile with PupGrade Joint Support. These veterinarian-recommended chews are made with a blend of glucosamine, chondroitin, MSM, and green-lipped mussel, all of which are essential for joint health. Your pup will love the taste, and you'll love knowing that they're getting the nutrients they need to stay healthy.
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“I'm thrilled with the results from Pupgrade’s Joint Support dog chews! Now that my dog is almost 7 years old, I really want to focus on his joints. My dog's mobility has improved significantly since starting these supplements. The meat-flavored chews make it enjoyable for my dog to take them! They're literally irresistable! The inclusion of Perna, known for its joint health benefits, adds an extra boost to the effectiveness of this product. I highly recommend it for any dog in need of joint support!”

- Victoria Peña

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Pupgrade Joint Support

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