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9/10 Dog Parents Reported An Improvement In Their Dog's Mobility

Crafted with love and backed by science, our treats boast a potent blend of ingredients like glucosamine, chondroitin, MSM, and green-lipped mussel. These elements work in harmony to nurture joint health, support cartilage regeneration and provide relief from the discomfort your furry companion might be silently enduring. This isn't just our promise – it's a shared experience. A whopping 90% of dog owners have seen incredible improvements in their canine friend's mobility.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Perna, glucosamine, MSM, DMG, and antioxidants for advanced joint support in canines. Greenfield Animal Hospital. (n.d.). Retrieved from https://greenfieldvets.com/
Perna: VCA Animal Hospital. Vca. (n.d.). Retrieved from https://vcahospitals.com/know-your-pet/perna#:~:text=What%20is%20perna%3F,cats%2C%20dogs%2C%20and%20horses.
Kim, L. S., Axelrod, L. J., Howard, P., Buratovich, N., & Waters , R. F. (n.d.). Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: A pilot clinical trial. Osteoarthritis and cartilage. Retrieved from https://pubmed.ncbi.nlm.nih.gov/16309928/
Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and chondroitin use in canines for osteoarthritis: A Review. Open veterinary journal. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356289/
Bierer, T. L., & Bui, L. M. (2002, June 1). Improvement of arthritic signs in dogs fed green-lipped mussel (Perna canaliculus). OUP Academic. Retrieved from https://academic.oup.com/jn/article/132/6/1634S/4687864
Debbi, E. M., Agar, G., Fichman, G., Ziv, Y. B., Kardosh, R., Halperin, N., Elbaz, A., Beer, Y., & Debi, R. (2011, June 27). Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: A randomized controlled study. BMC complementary and alternative medicine. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141601/
Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017, March 16). Methylsulfonylmethane: Applications and safety of a novel dietary supplement. Nutrients. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
Kabil O, Vitvitsky V, Banerjee R. Sulfur as a signaling nutrient through hydrogen sulfide. Annu Rev Nutr. 2014;34:171-205. doi: 10.1146/annurev-nutr-071813-105654. PMID: 25033061; PMCID: PMC4684266. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684266/
Whitehouse, M. W., Macrides, T. A., Kalafatis, N., Betts, W. H., Haynes, D. R., & Broadbent, J. (1997). Anti-inflammatory activity of a lipid fraction (lyprinol) from the NZ green-lipped mussel. Inflammopharmacology, 5(3), 237–246. https://doi.org/10.1007/s10787-997-0002-0

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Perna, glucosamine, MSM, DMG, and antioxidants for advanced joint support in canines. Greenfield Animal Hospital. (n.d.). Retrieved from https://greenfieldvets.com/
Perna: VCA Animal Hospital. Vca. (n.d.). Retrieved from https://vcahospitals.com/know-your-pet/perna#:~:text=What%20is%20perna%3F,cats%2C%20dogs%2C%20and%20horses.
Kim, L. S., Axelrod, L. J., Howard, P., Buratovich, N., & Waters , R. F. (n.d.). Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: A pilot clinical trial. Osteoarthritis and cartilage. Retrieved from https://pubmed.ncbi.nlm.nih.gov/16309928/
Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and chondroitin use in canines for osteoarthritis: A Review. Open veterinary journal. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356289/
Bierer, T. L., & Bui, L. M. (2002, June 1). Improvement of arthritic signs in dogs fed green-lipped mussel (Perna canaliculus). OUP Academic. Retrieved from https://academic.oup.com/jn/article/132/6/1634S/4687864
Debbi, E. M., Agar, G., Fichman, G., Ziv, Y. B., Kardosh, R., Halperin, N., Elbaz, A., Beer, Y., & Debi, R. (2011, June 27). Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: A randomized controlled study. BMC complementary and alternative medicine. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141601/
Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017, March 16). Methylsulfonylmethane: Applications and safety of a novel dietary supplement. Nutrients. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
Kabil O, Vitvitsky V, Banerjee R. Sulfur as a signaling nutrient through hydrogen sulfide. Annu Rev Nutr. 2014;34:171-205. doi: 10.1146/annurev-nutr-071813-105654. PMID: 25033061; PMCID: PMC4684266. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684266/
Whitehouse, M. W., Macrides, T. A., Kalafatis, N., Betts, W. H., Haynes, D. R., & Broadbent, J. (1997). Anti-inflammatory activity of a lipid fraction (lyprinol) from the NZ green-lipped mussel. Inflammopharmacology, 5(3), 237–246. https://doi.org/10.1007/s10787-997-0002-0

As Featured In..

Did you know? A staggering 80% of
dogs over 8 develop joint issues!

While other dog joint supplements mainly use Omega-3s, they lack the extra hydration provided by Perna Canaliculus.

Perna is a Green-lipped mussel from the shores of New Zealand, 100x+ more powerful than Omega-3 alone. It is naturally rich in Glucosamine, Chondroitin, Hyaluronic acid, EFAs, and Amino acids – a perfect blend for not just healing but also for joint issue prevention.

Let's look at some simple visual comparisons to see how effective our Perna Canaliculus formula is:

Damaged Cartilage

The deterioration of this vital cushioning tissue can lead to pain, restricted joint movement, and general discomfort

Loosen Ligament

As dogs age, the collagen and connective tissues in their joints may undergo changes, leading to reduced elasticity and firmness in the ligaments.

Synovial Inflammation

Aging can lead to a reduction in lubrication, which may result in less production of synovial fluid and increased friction within the joint.

Ligament

Perna supports optimal joint hydration, which promote the elasticity and strength of ligaments, therefore reducing the risk of strain and injury.

Cartilage

Our powerful blend of ingredients, including glucosamine and chondroitin, aids in the reconstruction of damaged cartilage.

Synovium

Our formula has anti-inflammatory and highly lubricant properties that reduce inflammation in the synovium and improve mobility.

Easily Digestible Ingredients

Nothing to hide here! Our recipe is suitable for even sensitive stomachs.

Safflower Oil

Healthy fat source for skin and coat

Brewer’s Yeast

A natural source of B-vitamins and minerals

Potato Flour

Easily digestible carbohydrate alternative

Cooked Beef

High-quality protein source and flavor

Purified Water

Essential for the formation and texture

Soy Lecithin

For better texture and nutrient absorption

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Picture-Perfect Moments From Our Customers

218 Happy Customers Reviews

If your dogs is having joint problems and didn’t like any of the other joint supplements you got before, this is your sign to buy PupGrade's Joint Support! I’ve never seen my dog runs so fast to get a "treat" before. He loves the meaty flavor and I love that the formula actually works! The best part: we noticed significant results after few weeks taking it everyday. Me and my dog Rio absolutely love and recommend it!

Barbara Lewis

I🐶 "Finally, a Joint Supplement my Dog Actually Enjoys!" I've tried several joint supplements for my Shih Tzu, but they were either ineffective or unappetizing. That's when I discovered this one from PupGrade, and it's been working! Joint Support's meat-flavored chews are an absolute hit with my little guy. He was starting to not want to take the stairs, but within a month I noticed an improvement in his mobility. He's running up the stairs again and he still has the energy to jump onto his favorite spot on the couch. PupGrade, you've won over both of our hearts! ❤️🐶

Adam Gagliardo

I have a four-year-old pup who, even though he’s a young guy, could 100% use the extra supplementary support that PupGrade’s Joint Support Chews provide. He’s a zoomy ball of energy, so I worry about his joints when he’s older. I was sold on these chews when I read about their natural ingredients - things like MSM, Glucosamine, Chondroitin, and Green-Lipped Mussels - which are so great for doggy mobility. These chews make it easy to protect my pup from future joint ouchies (and he absolutely loves them).

Marge Hynes

I'm thrilled with the results from Pupgrade’s Joint Support dog chews! Now that my dog is almost 7 years old, I really want to focus on his joints. My dog's mobility has improved significantly since starting these supplements. The meat-flavored chews make it enjoyable for my dog to take them! They're literally irresistable! The inclusion of Perna, known for its joint health benefits, adds an extra boost to the effectiveness of this product. I highly recommend it for any dog in need of joint support!

Victoria Peña

I almost never write reviews, but was so excited about this product, I decided to take a moment. My 30 pound dog is 12 years old and we have literally walked well over 10,000 miles over his lifetime. Walk everyday, and we both love it. In past year, he has struggled a lot, to the point we not only walked so slowly, but barely walked a mile or 2 each day, which took forever. There were even days he was not excited to go, and went a bit reluctantly.

Kim Waldie

It actually works and actually tastes good! My dog, Sweet James turns 10 in July and watching him age has been hard. Hed lost his want and ability to move around and do the things we loved. Within a couple days of starting to take PupGrade's Joint Support, I noticed a difference in his mobility and within a month hes back to swimming and jumping on the couch like he used to. As an added bonus, he seriously gobbles these up and theres no fight getting him to take it, just tail wags. I cant express how grateful I am to have my best bud feeling back to his best self, thank you!

Jada Redmon

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218 Happy Customers Reviews

Why Keep Your Pups Waiting?

Give them the Gift of Health and Mobility with PupGrade!

Your guarantee for extra happiness and a longer journey together.

Our delicious chews are not only a treat your dog will adore, but they're also loaded with the perfect balance of nutrients to maintain their joints and hips in optimal condition, including: Glucosamine, Chondroitin, MSM, and Perna Canaliculus — all vital for supporting joint health.

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For All Dog Sizes

No Artificial Additives

100% Satisfaction Guaranteed

Happy Joints, Happy Dogs

Words from those who've transformed their dogs' lives with PupGrade

Feeding Recommendations

Suitable for dogs across breeds, sizes, and ages, PupGrade Joint Chews serve as a delightful treat during or after meals.

Suggested use by weight:

30 lbs

1 chew per day

60 lbs

2 chew per day

90 lb

3 chew per day

120 lbs

4 chew per day

150 lbs

5 chew per day

Frequently Asked Questions

Find the answers you need right here

WHAT IS PUPGRADE JOINT SUPPORT FOR? DOES IT HAVE THE CORRECT DOSAGE FOR MY DOG’S NEEDS?

PupGrade Joint Support is a chewable supplement for dogs and puppies of all breeds, sizes, ages, and activity levels. Suitable for everyday canine health.

Our Joint Support is a research-backed formula with just the right amount of essential nutrients to help keep your pup mobile and lively.

HOW DO I FEED THIS SUPPLEMENT TO MY DOG?

We recommend following these directions for use:
1 Chew:
per 25 lbs.
Extra Support:
double dosage first 4 weeks.
1 Chew Daily:
divide between AM & PM.
*This product is intended for intermittent or supplemental feeding only.

IS THIS SUPPLEMENT FREE OF GRAIN?

We are a veterinarian-formulated brand you can trust. These chews are made with only the good stuff and are 100% junk free! We are proud to offer your pet savory, GMP-Certified chews free of grains, wheat, corn, artificial colors, dyes, or harmful preservatives.

HOW MANY CHEWS ARE IN THIS CONTAINER?

Our Joint Support supplements offer 60 chews per container.

WHAT ARE THE INGREDIENTS INCLUDED IN THIS PRODUCT?

Active Ingredients:
Glucosamine, Methyl Sulfonyl Methane, Green Lipped Mussel, Chondroitin, and Manganese Gluconate.
Additional Ingredients:
Brewer’s Yeast, Potato Flour, Can Molasses, Potato Starch, Purified Water, Soy Lecithin, Glycerin, Cooked Beef, Safflower Oil, Duck Flavor, Vitamin E, Ascorbic Acid, Sorbic Acid, Mixed Tocopherols.

WHAT IS THE GUARANTEED ANALYSIS PER CHEW (5g)?

Calories:
18 Kcal
Crude Protein (Min):
18%
Crude Fat (Min):
12%
Crude Fiber (Max):
3%
Moisture (Max):
8%

ARE THESE CHEWS SAFE FOR MY DOG IF THEY HAVE SENSITIVITIES OR OTHER CONDITIONS?

We understand that every dog has unique needs. That’s why we offer supplements tailored to address specific concerns, such as sensitive stomachs and diabetic conditions. Our supplements contain easily digestible ingredients and exclude common allergens. Consult with your veterinarian before giving this supplement to your dog if you have any concerns.

HOW DO I STORE THIS PRODUCT?

Store in a cool, dry place. Ensure container lid is securely closed after each use.

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